hrp0092lb-1 | Late Breaking Posters | ESPE2019

A Trial Investigating the Long-Term Efficacy and Safety of Two Doses of Norditropin® (Somatropin; Recombinant Human Growth Hormone) in Japanese Children with Short Stature Due to Noonan Syndrome Over Four Years of Treatment

Horikawa Reiko , Ogata Tsutomu , Matsubara Yoichi , Yokoya Susumu , Ogawa Yoshihisa , Nishijima Keiji , Endo Takaaki , Ozono Keiichi

Objectives: This trial (NCT01927861) evaluated the growth-promoting effect and safety of Norditropin® (somatropin; recombinant human growth hormone) in Japanese children with short stature due to Noonan syndrome over four years of treatment.Methods: Pre-pubertal children diagnosed with Noonan syndrome were randomized 1:1 to receive Norditropin® 0.033 mg/kg/day or 0.066 mg/kg/day. Change in...

hrp0092p1-243 | Multisystem Endocrine Disorders | ESPE2019

A Nation-Wide Questionnaire Survey Targeting Japanese Pediatric Endocrinologists Regarding Transitional Care in Pediatric and Adolescent Cancer Patients

Miyoshi Yoko , Yorifuji Tohru , Yokoya Susumu , Nagasaki Keisuke , Kawai Masanobu , Ishiguro Hiroyuki , Okada Satoshi , Kanno Junko , Takubo Noriyuki , Muroya Koji , Ito Junko , Horikawa Reiko , Shimizu Chikako , Ozono Keiichi

Background: While existing guidelines recommend long-term follow-up of childhood cancer survivors (CCS), transitional care among pediatric and adult endocrinologists has not been established in Japan.Objective and Hypotheses: To know the present situation and to cultivate a better understanding, we had conducted a nation-wide survey targeting Japanese pediatric endocrinologists.Method</stro...

hrp0086p2-p387 | Gonads &amp; DSD P2 | ESPE2016

Questionnaire Surveys Targeting Japanese Pediatric Endocrinologists Regarding Reproduction in Pediatric and Adolescent Cancer Patients

Miyoshi Yoko , Yorifuji Tohru , Horikawa Reiko , Takahashi Ikuko , Nagasaki Keisuke , Ishiguro Hiroyuki , Fujiwara Ikuma , Ito Junko , Yokoya Susumu , Ogata Tsutomu , Ozono Keiichi

Background: While existing guidelines recommend long-term follow-up of childhood cancer survivors (CCS), their fertility has not been clarified in Japan.Objective and hypotheses: To address this issue, we organized a working panel to compile evidence from CCSs. The team consisted of various medical specialists in foundation hospitals.Method: We had conducted the questionnaire surveys targeting pediatric endocrinologists regarding r...